Standard AIF

AIF

The computed arterial input function.

Model Selection
Select the AIF model to use.
Values: Parker (default), Weinmann.
Parker model [2]: Uses parameters derived by Parker et al. for high-temporal-resolution AIF modeling.
Weinmann model [1]: Uses parameters based on Weinmann et al.’s pharmacokinetic analysis.

Dose [mmol/kg] Float
The bolus dose injected in mmol per kg of body weight.
Default: 0.1

Duration [s] Float
Duration of the AIF in seconds.
Default: 300 s

Sampling Time [s] Float
Time interval between successive samples of the AIF curve.
Default: 5 s

Bolus Arrival Time [s] Float
The time at which the bolus arrives.
Default: 30 s

Peak amplitude, A1, [mM] Float
Amplitude of the main peak.

Peak width, Sigma1, [min] Float
Standard deviation (width) of the main peak.

Peak time, T1, [min] Float
Time at the center of the main peak.

Recirculation peak amplitude, A2, [mM] Float
Amplitude of the recirculation peak.

Recirculation peak width, Sigma2, [min] Float
Standard deviation (width) of the recirculation peak.

Recirculation peak time, T2, [min] Float
Time at the center of the recirculation peak.

Tail amplitude, Alpha, [mM] Float
Amplitude of the concentration in the tail.

Tail drop-off, Beta, [min⁻¹] Float
Rate at which the tail concentration drops.

Tail raise, s, [min⁻¹] Float
Speed at which the tail rises at bolus arrival.

Tail delay time, tau, [min] Float
Delay before the tail begins to rise.

Large vessel Hematocrit, Hct Float
Hematocrit value used in the model.

First amplitude, a1, [kg/liter] Float
First amplitude parameter.

Second amplitude, a2, [kg/liter] Float
Second amplitude parameter.

First clearance rate, m1, [min⁻¹] Float
First clearance rate.

Second clearance rate, m2, [min⁻¹] Float
Second clearance rate.